BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT
dihydronicotinamide-adenine dinucleotide, disodium salt
CAS: 606-68-8
Molecular Formula: C21H30N7NaO14P2
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT - Names and Identifiers
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT - Physico-chemical Properties
| Molecular Formula | C21H30N7NaO14P2 |
| Molar Mass | 689.44 |
| Density | 1.955 at 20℃ |
| Melting Point | 140-142°C |
| Water Solubility | soluble |
| Solubility | Dissolve in water. |
| Vapor Presure | 0.73Pa at 20-50℃ |
| Appearance | Odor-free light yellow powder |
| Color | Yellow |
| BRN | 5230241 |
| PH | 7.5 (100mg/mL in water, ±0.5) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | `sensitive` to light and easy to absorb moisture |
| MDL | MFCD00036200 |
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R39/23/24/25 - R40 - Limited evidence of a carcinogenic effect R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10-23 |
| TSCA | Yes |
| HS Code | 29349990 |
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT - Reference
| Reference Show more | 1. Wei Hao Hua Zhang Hongling Li Xingtai. Protective Effect of crude polysaccharides from sea cucumber Apostichopus japonicus on mitochondria and its mechanism [J]. Science and Technology of Food Industry 2018 039(020):280-285. 2. Ji Shujuan, Shen Yixiao, Zhang Liping, bu Qingcheng. Effects of 1-methylcyclopropene treatment (1-MCP) on Esters, amino acids and related metabolic enzymes of Nanguo pear [J]. Food Science, 2012, 33(18):286-289. 3. Ma Cheng, Liang, Qi, Wen, Pengcheng, et al. Effect of modified atmosphere packaging on color stability of yak meat [J]. Food and Fermentation Industries 2016 42(009):130-136. 4. Zhou Xin, Dong Ling, Ji Shujuan. Changes of Ester aroma and related gene expression induced by intermittent heating during cold storage and normal temperature transformation of Nanguo pear [J]. Food Science, 2015, 29 (14):206-211. 5. Shao Jingxuan, Gao Xiaoge, Wang Yanan, etc. Changes of antioxidant peptide activity during processing of Xuanwei ham [J]. Science and Technology of food industry, 2019, 040(001):101-104,208. 6. Zhang Yubin, Li Pingzi, Lei Yun, etc. Study on NADH mitochondria-mediated regeneration of yak meat based on lactate-LDH [J]. Journal of Agricultural Machinery, 2020, v.51(06):360-366. 7. Zhang Liping, Ji Shujuan. Effects of ethephon on aroma and key enzyme activities during aroma synthesis of Nanguo pear treated with 1-MCP during cold storage [J]. Food Science, 2013, 34(10):294-298. 8. Duan, Yajie, et al. "Antifungal mechanism of Streptomyces ma. FS‐4 on fusarium wilt of banana." Journal of Applied Microbiology 130.1 (2021): 196-207. 9. Zheng, S., Zhang, Q., Yin, D. et al. NADPH-guided synthesis of iodide-responsive nanozyme: synergistic effects in nanocluster growth and peroxidase-like activity. J Mater Sci 56, 4909-4921 (2021). https://doi.org/10.1007/s10853-020-05589-0 10. [IF=3.757] Die Hu et al."Characterization of a robust glucose 1-dehydrogenase, SyGDH, and its application in NADPH regeneration for the asymmetric reduction of haloketone by a carbonyl reductase in organic solvent/buffer system."Process Biochem. 2020 Feb;89:55 |
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT - Reference Information
| Update Date: | 2022/11/12 10:05:38 |
| LogP | -1.96 at 21℃ and pH7 |
| surface tension | 69.22mN/m at 1.022g/L and 20 ℃ |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | nicotinamide adenine dinucleotide is a coenzyme that transmits protons, more precisely hydrogen ions, it occurs in many metabolic reactions in cells. NADH or more precisely NADH H is its reduced form. It can be reduced to carry up to two protons (written as NADH H). |
| Use | beta-nicotinamide adenine dinucleotide disodium is a biologically active form of nicotinic acid. Used as a coenzyme for hydrogenase and dehydrogenase. NAD typically acts as a hydrogen acceptor, forming NADH, which then acts as a hydrogen donor in the respiratory chain. It is present primarily in the reduced form (NADPH) in living cells and participates in synthetic reactions. Two forms occur, α-NAD and β-NAD, which are characterized by the configuration of the ribonicotinamide bond. Only the β-anomaly has biological activity. β-nicotinamide adenine dinucleotide (NAD) and reduced β-nicotinamide adenine dinucleotide (NADH), composed of a coenzyme redox pair (NAD :NADH) involved in a wide range of enzyme-catalyzed redox reactions; And its redox function, in ADP-ribosylation (ADP-ribosyltransferase, polymerization (ADP-ribose polymerase) reaction) is a ADP-ribose donor unit; and a periodic ADP-ribose (ADP-ribose cyclase) precursor Electron donor |
| biological activity | NADH is a coenzyme in catabolic processes such as glycolysis, the beta oxidation and the tricarboxylic acid cycle are regenerative electron donors. |
Last Update：2024-04-29 13:12:03
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View History
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT
对甲苯磺酰脲
1beta-Hydroxyethyl-4-nitropyrazole
N-(2-羟乙基)-4,6-二甲基-3-氰基吡啶酮
对戊氧基苯甲酸
培美曲塞
2,2-dlethoxyaceticacidethylester
2-Hydroxyoleanolic acid
Methyl 5-bromo-2-iodobenzoate
4,6-DICHLOROPICOLINIC ACID
对甲苯磺酰脲
1beta-Hydroxyethyl-4-nitropyrazole
N-(2-羟乙基)-4,6-二甲基-3-氰基吡啶酮
对戊氧基苯甲酸
培美曲塞
2,2-dlethoxyaceticacidethylester
2-Hydroxyoleanolic acid
Methyl 5-bromo-2-iodobenzoate
4,6-DICHLOROPICOLINIC ACID